AustralieFrV1, Main, Exploration, bibRecord, 001856

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

Identifieur interne : 001856 ( Main/Exploration ); précédent : 001855; suivant : 001857

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

Auteurs : Jonathan Ac Sterne [Royaume-Uni] ; Miguel A. Hernán [États-Unis] ; Barnaby C. Reeves [Royaume-Uni] ; Jelena Savovi [Royaume-Uni] ; Nancy D. Berkman [États-Unis] ; Meera Viswanathan [États-Unis] ; David Henry [Canada] ; Douglas G. Altman [Royaume-Uni] ; Mohammed T. Ansari [Canada] ; Isabelle Boutron [France] ; James R. Carpenter [Royaume-Uni] ; An-Wen Chan [Canada] ; Rachel Churchill [Royaume-Uni] ; Jonathan J. Deeks [Royaume-Uni] ; Asbj Rn Hr Bjartsson [Danemark] ; Jamie Kirkham [Royaume-Uni] ; Peter Jüni [Canada] ; Yoon K. Loke [Royaume-Uni] ; Theresa D. Pigott [États-Unis] ; Craig R. Ramsay [Royaume-Uni] ; Deborah Regidor [États-Unis] ; Hannah R. Rothstein [États-Unis] ; Lakhbir Sandhu [Canada] ; Pasqualina L. Santaguida [Canada] ; Holger J. Schünemann [Canada] ; Beverly Shea [Canada] ; Ian Shrier [Canada] ; Peter Tugwell [Canada] ; Lucy Turner [Canada] ; Jeffrey C. Valentine [États-Unis] ; Hugh Waddington [Royaume-Uni] ; Elizabeth Waters [Australie] ; George A. Wells [Canada] ; Penny F. Whiting [Royaume-Uni] ; Julian Pt Higgins [Royaume-Uni]

Source :

The BMJ [ 0959-8138 ] ; 2016.

RBID : PMC:5062054

Descripteurs français

KwdFr :
- Biais (épidémiologie), Essais cliniques comme sujet, Facteurs de confusion (épidémiologie), Humains, Projets pilotes, Risque, Statistiques comme sujet (instrumentation), Étude d'observation comme sujet.
MESH :
- instrumentation : Biais (épidémiologie), Essais cliniques comme sujet, Facteurs de confusion (épidémiologie), Humains, Projets pilotes, Risque, Statistiques comme sujet, Étude d'observation comme sujet.

English descriptors

KwdEn :
- Bias (Epidemiology), Clinical Trials as Topic, Confounding Factors (Epidemiology), Humans, Observational Studies as Topic, Pilot Projects, Risk, Statistics as Topic (instrumentation).
MESH :
- instrumentation : Statistics as Topic.
- Bias (Epidemiology), Clinical Trials as Topic, Confounding Factors (Epidemiology), Humans, Observational Studies as Topic, Pilot Projects, Risk.

Abstract

Non-randomised studies of the effects of interventions are critical to many areas of healthcare evaluation, but their results may be biased. It is therefore important to understand and appraise their strengths and weaknesses. We developed ROBINS-I (“Risk Of Bias In Non-randomised Studies - of Interventions”), a new tool for evaluating risk of bias in estimates of the comparative effectiveness (harm or benefit) of interventions from studies that did not use randomisation to allocate units (individuals or clusters of individuals) to comparison groups. The tool will be particularly useful to those undertaking systematic reviews that include non-randomised studies.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062054

DOI: 10.1136/bmj.i4919
PubMed: 27733354
PubMed Central: 5062054

Affiliations:

Le document en format XML

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<author><name sortKey="Deeks, Jonathan J" sort="Deeks, Jonathan J" uniqKey="Deeks J" first="Jonathan J" last="Deeks">Jonathan J. Deeks</name>
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<author><name sortKey="Pigott, Theresa D" sort="Pigott, Theresa D" uniqKey="Pigott T" first="Theresa D" last="Pigott">Theresa D. Pigott</name>
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<author><name sortKey="Ramsay, Craig R" sort="Ramsay, Craig R" uniqKey="Ramsay C" first="Craig R" last="Ramsay">Craig R. Ramsay</name>
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<author><name sortKey="Regidor, Deborah" sort="Regidor, Deborah" uniqKey="Regidor D" first="Deborah" last="Regidor">Deborah Regidor</name>
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<placeName><region type="state">Californie</region>
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<author><name sortKey="Rothstein, Hannah R" sort="Rothstein, Hannah R" uniqKey="Rothstein H" first="Hannah R" last="Rothstein">Hannah R. Rothstein</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Management, Zicklin School of Business, Baruch College—CUNY, New York, NY 10010, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Management, Zicklin School of Business, Baruch College—CUNY, New York, NY 10010</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sandhu, Lakhbir" sort="Sandhu, Lakhbir" uniqKey="Sandhu L" first="Lakhbir" last="Sandhu">Lakhbir Sandhu</name>
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<orgName type="university">Université de Toronto</orgName>
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<author><name sortKey="Santaguida, Pasqualina L" sort="Santaguida, Pasqualina L" uniqKey="Santaguida P" first="Pasqualina L" last="Santaguida">Pasqualina L. Santaguida</name>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, L8S 4K1</wicri:regionArea>
<orgName type="university">Université McMaster</orgName>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
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</placeName>
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<author><name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. Schünemann</name>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>Departments of Clinical Epidemiology and Biostatistics and of Medicine, Cochrane Applicability and Recommendations Methods (GRADEing) Group, MacGRADE center, Ontario, L8N 4K1</wicri:regionArea>
<wicri:noRegion>L8N 4K1</wicri:noRegion>
</affiliation>
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<author><name sortKey="Shea, Beverly" sort="Shea, Beverly" uniqKey="Shea B" first="Beverly" last="Shea">Beverly Shea</name>
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<country xml:lang="fr">Canada</country>
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<author><name sortKey="Shrier, Ian" sort="Shrier, Ian" uniqKey="Shrier I" first="Ian" last="Shrier">Ian Shrier</name>
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<wicri:regionArea>Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec</wicri:regionArea>
<orgName type="university">Université McGill</orgName>
<placeName><settlement type="city">Montréal</settlement>
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<author><name sortKey="Tugwell, Peter" sort="Tugwell, Peter" uniqKey="Tugwell P" first="Peter" last="Tugwell">Peter Tugwell</name>
<affiliation wicri:level="1"><nlm:aff id="aff28">Department of Medicine and School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada</nlm:aff>
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<wicri:regionArea>Department of Medicine and School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario</wicri:regionArea>
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<author><name sortKey="Turner, Lucy" sort="Turner, Lucy" uniqKey="Turner L" first="Lucy" last="Turner">Lucy Turner</name>
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<author><name sortKey="Valentine, Jeffrey C" sort="Valentine, Jeffrey C" uniqKey="Valentine J" first="Jeffrey C" last="Valentine">Jeffrey C. Valentine</name>
<affiliation wicri:level="2"><nlm:aff id="aff30">University of Louisville, Louisville, KY 40292, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of Louisville, Louisville, KY 40292</wicri:regionArea>
<placeName><region type="state">Kentucky</region>
</placeName>
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</author>
<author><name sortKey="Waddington, Hugh" sort="Waddington, Hugh" uniqKey="Waddington H" first="Hugh" last="Waddington">Hugh Waddington</name>
<affiliation wicri:level="3"><nlm:aff id="aff31">International Initiative for Impact Evaluation, London School of Hygiene and Tropical Medicine, and London International Development Centre, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>International Initiative for Impact Evaluation, London School of Hygiene and Tropical Medicine, and London International Development Centre, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
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<author><name sortKey="Waters, Elizabeth" sort="Waters, Elizabeth" uniqKey="Waters E" first="Elizabeth" last="Waters">Elizabeth Waters</name>
<affiliation wicri:level="4"><nlm:aff id="aff32">Jack Brockhoff Child Health & Wellbeing Program, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Jack Brockhoff Child Health & Wellbeing Program, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
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<author><name sortKey="Wells, George A" sort="Wells, George A" uniqKey="Wells G" first="George A" last="Wells">George A. Wells</name>
<affiliation wicri:level="1"><nlm:aff id="aff33">School of Epidemiology, Public Health and Preventive Medicine and Director, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>School of Epidemiology, Public Health and Preventive Medicine and Director, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7</wicri:regionArea>
<wicri:noRegion>K1Y 4W7</wicri:noRegion>
</affiliation>
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<author><name sortKey="Whiting, Penny F" sort="Whiting, Penny F" uniqKey="Whiting P" first="Penny F" last="Whiting">Penny F. Whiting</name>
<affiliation wicri:level="1"><nlm:aff id="aff34">School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS, UK; and National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West) at University Hospitals Bristol NHS Foundation Trust, Bristol BS1 2NT, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
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</author>
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<affiliation wicri:level="1"><nlm:aff id="aff35">School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions</title>
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<country xml:lang="fr">Royaume-Uni</country>
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<affiliation wicri:level="2"><nlm:aff id="aff2">Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; and Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; and Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, Massachusetts</wicri:regionArea>
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<author><name sortKey="Reeves, Barnaby C" sort="Reeves, Barnaby C" uniqKey="Reeves B" first="Barnaby C" last="Reeves">Barnaby C. Reeves</name>
<affiliation wicri:level="1"><nlm:aff id="aff3">School of Clinical Sciences, University of Bristol, Bristol, BS2 8HW, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Clinical Sciences, University of Bristol, Bristol, BS2 8HW</wicri:regionArea>
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</author>
<author><name sortKey="Savovi, Jelena" sort="Savovi, Jelena" uniqKey="Savovi J" first="Jelena" last="Savovi">Jelena Savovi</name>
<affiliation><nlm:aff>NONE</nlm:aff>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff4">National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West) at University Hospitals Bristol NHS Foundation Trust, Bristol BS1 2NT, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West) at University Hospitals Bristol NHS Foundation Trust, Bristol BS1 2NT</wicri:regionArea>
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</affiliation>
</author>
<author><name sortKey="Berkman, Nancy D" sort="Berkman, Nancy D" uniqKey="Berkman N" first="Nancy D" last="Berkman">Nancy D. Berkman</name>
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<country xml:lang="fr">États-Unis</country>
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</placeName>
</affiliation>
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<author><name sortKey="Viswanathan, Meera" sort="Viswanathan, Meera" uniqKey="Viswanathan M" first="Meera" last="Viswanathan">Meera Viswanathan</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">RTI-UNC Evidence-based Practice Center, RTI International, Research Triangle Park, NC 27709, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>RTI-UNC Evidence-based Practice Center, RTI International, Research Triangle Park, NC 27709</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Henry, David" sort="Henry, David" uniqKey="Henry D" first="David" last="Henry">David Henry</name>
<affiliation wicri:level="4"><nlm:aff id="aff7">Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Altman, Douglas G" sort="Altman, Douglas G" uniqKey="Altman D" first="Douglas G" last="Altman">Douglas G. Altman</name>
<affiliation wicri:level="4"><nlm:aff id="aff8">Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD</wicri:regionArea>
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</placeName>
</affiliation>
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<author><name sortKey="Ansari, Mohammed T" sort="Ansari, Mohammed T" uniqKey="Ansari M" first="Mohammed T" last="Ansari">Mohammed T. Ansari</name>
<affiliation wicri:level="1"><nlm:aff id="aff9">School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5</wicri:regionArea>
<wicri:noRegion>K1H 8M5</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Boutron, Isabelle" sort="Boutron, Isabelle" uniqKey="Boutron I" first="Isabelle" last="Boutron">Isabelle Boutron</name>
<affiliation wicri:level="3"><nlm:aff id="aff10">METHODS Team, Centre of Epidemiology and Statistics Sorbonne Paris Cité Research, INSERM UMR 1153, University Paris Descartes, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>METHODS Team, Centre of Epidemiology and Statistics Sorbonne Paris Cité Research, INSERM UMR 1153, University Paris Descartes, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carpenter, James R" sort="Carpenter, James R" uniqKey="Carpenter J" first="James R" last="Carpenter">James R. Carpenter</name>
<affiliation wicri:level="3"><nlm:aff id="aff11">Department of Medical Statistics, London School of Hygiene and Tropical Medicine and MRC Clinical Trials Unit at UCL, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Medical Statistics, London School of Hygiene and Tropical Medicine and MRC Clinical Trials Unit at UCL, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chan, An Wen" sort="Chan, An Wen" uniqKey="Chan A" first="An-Wen" last="Chan">An-Wen Chan</name>
<affiliation wicri:level="4"><nlm:aff id="aff12">Women's College Research Institute, Department of Medicine, University of Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Women's College Research Institute, Department of Medicine, University of Toronto</wicri:regionArea>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
<orgName type="university">Université de Toronto</orgName>
</affiliation>
</author>
<author><name sortKey="Churchill, Rachel" sort="Churchill, Rachel" uniqKey="Churchill R" first="Rachel" last="Churchill">Rachel Churchill</name>
<affiliation wicri:level="1"><nlm:aff id="aff13">Centre for Reviews and Dissemination, University of York, York, YO10 5DD, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Reviews and Dissemination, University of York, York, YO10 5DD</wicri:regionArea>
<wicri:noRegion>YO10 5DD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Deeks, Jonathan J" sort="Deeks, Jonathan J" uniqKey="Deeks J" first="Jonathan J" last="Deeks">Jonathan J. Deeks</name>
<affiliation wicri:level="4"><nlm:aff id="aff14">Institute of Applied Health Research, University of Birmingham, Birmingham B15 2TT, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Applied Health Research, University of Birmingham, Birmingham B15 2TT</wicri:regionArea>
<orgName type="university">Université de Birmingham</orgName>
<placeName><settlement type="city">Birmingham</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Midlands de l'Ouest</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hr Bjartsson, Asbj Rn" sort="Hr Bjartsson, Asbj Rn" uniqKey="Hr Bjartsson A" first="Asbj Rn" last="Hr Bjartsson">Asbj Rn Hr Bjartsson</name>
<affiliation wicri:level="1"><nlm:aff id="aff15">Center for Evidence-Based Medicine, University of Southern Denmark & Odense University Hospital, 5000 Odense C, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Center for Evidence-Based Medicine, University of Southern Denmark & Odense University Hospital, 5000 Odense C</wicri:regionArea>
<wicri:noRegion>5000 Odense C</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kirkham, Jamie" sort="Kirkham, Jamie" uniqKey="Kirkham J" first="Jamie" last="Kirkham">Jamie Kirkham</name>
<affiliation wicri:level="1"><nlm:aff id="aff16">Department of Biostatistics, University of Liverpool, Liverpool, L69 3GL, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Biostatistics, University of Liverpool, Liverpool, L69 3GL</wicri:regionArea>
<wicri:noRegion>L69 3GL</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Juni, Peter" sort="Juni, Peter" uniqKey="Juni P" first="Peter" last="Jüni">Peter Jüni</name>
<affiliation wicri:level="4"><nlm:aff id="aff17">Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St Michael’s Hospital, and Department of Medicine, University of Toronto, Toronto, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St Michael’s Hospital, and Department of Medicine, University of Toronto, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Loke, Yoon K" sort="Loke, Yoon K" uniqKey="Loke Y" first="Yoon K" last="Loke">Yoon K. Loke</name>
<affiliation wicri:level="1"><nlm:aff id="aff18">Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Norwich Medical School, University of East Anglia, Norwich NR4 7TJ</wicri:regionArea>
<wicri:noRegion>Norwich NR4 7TJ</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pigott, Theresa D" sort="Pigott, Theresa D" uniqKey="Pigott T" first="Theresa D" last="Pigott">Theresa D. Pigott</name>
<affiliation wicri:level="2"><nlm:aff id="aff19">School of Education, Loyola University Chicago, Chicago, IL 60611, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>School of Education, Loyola University Chicago, Chicago, IL 60611</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ramsay, Craig R" sort="Ramsay, Craig R" uniqKey="Ramsay C" first="Craig R" last="Ramsay">Craig R. Ramsay</name>
<affiliation wicri:level="1"><nlm:aff id="aff20">Health Services Research Unit, University of Aberdeen, Aberdeen, AB25 2ZD, UK.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country>
<wicri:regionArea>Health Services Research Unit, University of Aberdeen, Aberdeen, AB25 2ZD</wicri:regionArea>
<wicri:noRegion>AB25 2ZD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Regidor, Deborah" sort="Regidor, Deborah" uniqKey="Regidor D" first="Deborah" last="Regidor">Deborah Regidor</name>
<affiliation wicri:level="2"><nlm:aff id="aff21">Evidence Services, Kaiser Permanente, Care Management Institute, Oakland, CA 94612, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Evidence Services, Kaiser Permanente, Care Management Institute, Oakland, CA 94612</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rothstein, Hannah R" sort="Rothstein, Hannah R" uniqKey="Rothstein H" first="Hannah R" last="Rothstein">Hannah R. Rothstein</name>
<affiliation wicri:level="2"><nlm:aff id="aff22">Department of Management, Zicklin School of Business, Baruch College—CUNY, New York, NY 10010, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Management, Zicklin School of Business, Baruch College—CUNY, New York, NY 10010</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sandhu, Lakhbir" sort="Sandhu, Lakhbir" uniqKey="Sandhu L" first="Lakhbir" last="Sandhu">Lakhbir Sandhu</name>
<affiliation wicri:level="4"><nlm:aff id="aff23">Division of General Surgery, University of Toronto, Toronto, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of General Surgery, University of Toronto, Toronto</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Santaguida, Pasqualina L" sort="Santaguida, Pasqualina L" uniqKey="Santaguida P" first="Pasqualina L" last="Santaguida">Pasqualina L. Santaguida</name>
<affiliation wicri:level="4"><nlm:aff id="aff24">Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, L8S 4K1, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, L8S 4K1</wicri:regionArea>
<orgName type="university">Université McMaster</orgName>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. Schünemann</name>
<affiliation wicri:level="1"><nlm:aff id="aff25">Departments of Clinical Epidemiology and Biostatistics and of Medicine, Cochrane Applicability and Recommendations Methods (GRADEing) Group, MacGRADE center, Ontario, L8N 4K1, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Departments of Clinical Epidemiology and Biostatistics and of Medicine, Cochrane Applicability and Recommendations Methods (GRADEing) Group, MacGRADE center, Ontario, L8N 4K1</wicri:regionArea>
<wicri:noRegion>L8N 4K1</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shea, Beverly" sort="Shea, Beverly" uniqKey="Shea B" first="Beverly" last="Shea">Beverly Shea</name>
<affiliation wicri:level="1"><nlm:aff id="aff26">Ottawa Hospital Research Institute, Center for Practice Changing Research and School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Ottawa Hospital Research Institute, Center for Practice Changing Research and School of Epidemiology, Public Health and Preventive Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, K1H 8M5</wicri:regionArea>
<wicri:noRegion>K1H 8M5</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shrier, Ian" sort="Shrier, Ian" uniqKey="Shrier I" first="Ian" last="Shrier">Ian Shrier</name>
<affiliation wicri:level="4"><nlm:aff id="aff27">Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec</wicri:regionArea>
<orgName type="university">Université McGill</orgName>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tugwell, Peter" sort="Tugwell, Peter" uniqKey="Tugwell P" first="Peter" last="Tugwell">Peter Tugwell</name>
<affiliation wicri:level="1"><nlm:aff id="aff28">Department of Medicine and School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Medicine and School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Turner, Lucy" sort="Turner, Lucy" uniqKey="Turner L" first="Lucy" last="Turner">Lucy Turner</name>
<affiliation wicri:level="1"><nlm:aff id="aff29">Ottawa Hospital Research Institute, Ottawa, ON, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Ottawa Hospital Research Institute, Ottawa, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Valentine, Jeffrey C" sort="Valentine, Jeffrey C" uniqKey="Valentine J" first="Jeffrey C" last="Valentine">Jeffrey C. Valentine</name>
<affiliation wicri:level="2"><nlm:aff id="aff30">University of Louisville, Louisville, KY 40292, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of Louisville, Louisville, KY 40292</wicri:regionArea>
<placeName><region type="state">Kentucky</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Waddington, Hugh" sort="Waddington, Hugh" uniqKey="Waddington H" first="Hugh" last="Waddington">Hugh Waddington</name>
<affiliation wicri:level="3"><nlm:aff id="aff31">International Initiative for Impact Evaluation, London School of Hygiene and Tropical Medicine, and London International Development Centre, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>International Initiative for Impact Evaluation, London School of Hygiene and Tropical Medicine, and London International Development Centre, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Waters, Elizabeth" sort="Waters, Elizabeth" uniqKey="Waters E" first="Elizabeth" last="Waters">Elizabeth Waters</name>
<affiliation wicri:level="4"><nlm:aff id="aff32">Jack Brockhoff Child Health & Wellbeing Program, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC 3010, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Jack Brockhoff Child Health & Wellbeing Program, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC 3010</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wells, George A" sort="Wells, George A" uniqKey="Wells G" first="George A" last="Wells">George A. Wells</name>
<affiliation wicri:level="1"><nlm:aff id="aff33">School of Epidemiology, Public Health and Preventive Medicine and Director, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>School of Epidemiology, Public Health and Preventive Medicine and Director, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, K1Y 4W7</wicri:regionArea>
<wicri:noRegion>K1Y 4W7</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Whiting, Penny F" sort="Whiting, Penny F" uniqKey="Whiting P" first="Penny F" last="Whiting">Penny F. Whiting</name>
<affiliation wicri:level="1"><nlm:aff id="aff34">School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS, UK; and National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West) at University Hospitals Bristol NHS Foundation Trust, Bristol BS1 2NT, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS, UK; and National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West) at University Hospitals Bristol NHS Foundation Trust, Bristol BS1 2NT</wicri:regionArea>
<wicri:noRegion>Bristol BS1 2NT</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Higgins, Julian Pt" sort="Higgins, Julian Pt" uniqKey="Higgins J" first="Julian Pt" last="Higgins">Julian Pt Higgins</name>
<affiliation wicri:level="1"><nlm:aff id="aff35">School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS</wicri:regionArea>
<wicri:noRegion>Bristol BS8 2PS</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">The BMJ</title>
<idno type="ISSN">0959-8138</idno>
<idno type="eISSN">1756-1833</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bias (Epidemiology)</term>
<term>Clinical Trials as Topic</term>
<term>Confounding Factors (Epidemiology)</term>
<term>Humans</term>
<term>Observational Studies as Topic</term>
<term>Pilot Projects</term>
<term>Risk</term>
<term>Statistics as Topic (instrumentation)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Biais (épidémiologie)</term>
<term>Essais cliniques comme sujet</term>
<term>Facteurs de confusion (épidémiologie)</term>
<term>Humains</term>
<term>Projets pilotes</term>
<term>Risque</term>
<term>Statistiques comme sujet (instrumentation)</term>
<term>Étude d'observation comme sujet</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Statistics as Topic</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Bias (Epidemiology)</term>
<term>Clinical Trials as Topic</term>
<term>Confounding Factors (Epidemiology)</term>
<term>Humans</term>
<term>Observational Studies as Topic</term>
<term>Pilot Projects</term>
<term>Risk</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="fr"><term>Biais (épidémiologie)</term>
<term>Essais cliniques comme sujet</term>
<term>Facteurs de confusion (épidémiologie)</term>
<term>Humains</term>
<term>Projets pilotes</term>
<term>Risque</term>
<term>Statistiques comme sujet</term>
<term>Étude d'observation comme sujet</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Non-randomised studies of the effects of interventions are critical to many areas of healthcare evaluation, but their results may be biased. It is therefore important to understand and appraise their strengths and weaknesses. We developed ROBINS-I (“Risk Of Bias In Non-randomised Studies - of Interventions”), a new tool for evaluating risk of bias in estimates of the comparative effectiveness (harm or benefit) of interventions from studies that did not use randomisation to allocate units (individuals or clusters of individuals) to comparison groups. The tool will be particularly useful to those undertaking systematic reviews that include non-randomised studies.</p>
</div>
</front>
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<affiliations><list><country><li>Australie</li>
<li>Canada</li>
<li>Danemark</li>
<li>France</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Californie</li>
<li>Caroline du Nord</li>
<li>Grand Londres</li>
<li>Illinois</li>
<li>Kentucky</li>
<li>Massachusetts</li>
<li>Midlands de l'Ouest</li>
<li>Ontario</li>
<li>Oxfordshire</li>
<li>Québec</li>
<li>Victoria (État)</li>
<li>État de New York</li>
<li>Île-de-France</li>
</region>
<settlement><li>Birmingham</li>
<li>Hamilton (Ontario)</li>
<li>Londres</li>
<li>Melbourne</li>
<li>Montréal</li>
<li>Oxford</li>
<li>Paris</li>
<li>Toronto</li>
</settlement>
<orgName><li>Université McGill</li>
<li>Université McMaster</li>
<li>Université d'Oxford</li>
<li>Université de Birmingham</li>
<li>Université de Melbourne</li>
<li>Université de Toronto</li>
</orgName>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Sterne, Jonathan Ac" sort="Sterne, Jonathan Ac" uniqKey="Sterne J" first="Jonathan Ac" last="Sterne">Jonathan Ac Sterne</name>
</noRegion>
<name sortKey="Altman, Douglas G" sort="Altman, Douglas G" uniqKey="Altman D" first="Douglas G" last="Altman">Douglas G. Altman</name>
<name sortKey="Carpenter, James R" sort="Carpenter, James R" uniqKey="Carpenter J" first="James R" last="Carpenter">James R. Carpenter</name>
<name sortKey="Churchill, Rachel" sort="Churchill, Rachel" uniqKey="Churchill R" first="Rachel" last="Churchill">Rachel Churchill</name>
<name sortKey="Deeks, Jonathan J" sort="Deeks, Jonathan J" uniqKey="Deeks J" first="Jonathan J" last="Deeks">Jonathan J. Deeks</name>
<name sortKey="Higgins, Julian Pt" sort="Higgins, Julian Pt" uniqKey="Higgins J" first="Julian Pt" last="Higgins">Julian Pt Higgins</name>
<name sortKey="Kirkham, Jamie" sort="Kirkham, Jamie" uniqKey="Kirkham J" first="Jamie" last="Kirkham">Jamie Kirkham</name>
<name sortKey="Loke, Yoon K" sort="Loke, Yoon K" uniqKey="Loke Y" first="Yoon K" last="Loke">Yoon K. Loke</name>
<name sortKey="Ramsay, Craig R" sort="Ramsay, Craig R" uniqKey="Ramsay C" first="Craig R" last="Ramsay">Craig R. Ramsay</name>
<name sortKey="Reeves, Barnaby C" sort="Reeves, Barnaby C" uniqKey="Reeves B" first="Barnaby C" last="Reeves">Barnaby C. Reeves</name>
<name sortKey="Savovi, Jelena" sort="Savovi, Jelena" uniqKey="Savovi J" first="Jelena" last="Savovi">Jelena Savovi</name>
<name sortKey="Waddington, Hugh" sort="Waddington, Hugh" uniqKey="Waddington H" first="Hugh" last="Waddington">Hugh Waddington</name>
<name sortKey="Whiting, Penny F" sort="Whiting, Penny F" uniqKey="Whiting P" first="Penny F" last="Whiting">Penny F. Whiting</name>
</country>
<country name="États-Unis"><region name="Massachusetts"><name sortKey="Hernan, Miguel A" sort="Hernan, Miguel A" uniqKey="Hernan M" first="Miguel A" last="Hernán">Miguel A. Hernán</name>
</region>
<name sortKey="Berkman, Nancy D" sort="Berkman, Nancy D" uniqKey="Berkman N" first="Nancy D" last="Berkman">Nancy D. Berkman</name>
<name sortKey="Pigott, Theresa D" sort="Pigott, Theresa D" uniqKey="Pigott T" first="Theresa D" last="Pigott">Theresa D. Pigott</name>
<name sortKey="Regidor, Deborah" sort="Regidor, Deborah" uniqKey="Regidor D" first="Deborah" last="Regidor">Deborah Regidor</name>
<name sortKey="Rothstein, Hannah R" sort="Rothstein, Hannah R" uniqKey="Rothstein H" first="Hannah R" last="Rothstein">Hannah R. Rothstein</name>
<name sortKey="Valentine, Jeffrey C" sort="Valentine, Jeffrey C" uniqKey="Valentine J" first="Jeffrey C" last="Valentine">Jeffrey C. Valentine</name>
<name sortKey="Viswanathan, Meera" sort="Viswanathan, Meera" uniqKey="Viswanathan M" first="Meera" last="Viswanathan">Meera Viswanathan</name>
</country>
<country name="Canada"><region name="Ontario"><name sortKey="Henry, David" sort="Henry, David" uniqKey="Henry D" first="David" last="Henry">David Henry</name>
</region>
<name sortKey="Ansari, Mohammed T" sort="Ansari, Mohammed T" uniqKey="Ansari M" first="Mohammed T" last="Ansari">Mohammed T. Ansari</name>
<name sortKey="Chan, An Wen" sort="Chan, An Wen" uniqKey="Chan A" first="An-Wen" last="Chan">An-Wen Chan</name>
<name sortKey="Juni, Peter" sort="Juni, Peter" uniqKey="Juni P" first="Peter" last="Jüni">Peter Jüni</name>
<name sortKey="Sandhu, Lakhbir" sort="Sandhu, Lakhbir" uniqKey="Sandhu L" first="Lakhbir" last="Sandhu">Lakhbir Sandhu</name>
<name sortKey="Santaguida, Pasqualina L" sort="Santaguida, Pasqualina L" uniqKey="Santaguida P" first="Pasqualina L" last="Santaguida">Pasqualina L. Santaguida</name>
<name sortKey="Schunemann, Holger J" sort="Schunemann, Holger J" uniqKey="Schunemann H" first="Holger J" last="Schünemann">Holger J. Schünemann</name>
<name sortKey="Shea, Beverly" sort="Shea, Beverly" uniqKey="Shea B" first="Beverly" last="Shea">Beverly Shea</name>
<name sortKey="Shrier, Ian" sort="Shrier, Ian" uniqKey="Shrier I" first="Ian" last="Shrier">Ian Shrier</name>
<name sortKey="Tugwell, Peter" sort="Tugwell, Peter" uniqKey="Tugwell P" first="Peter" last="Tugwell">Peter Tugwell</name>
<name sortKey="Turner, Lucy" sort="Turner, Lucy" uniqKey="Turner L" first="Lucy" last="Turner">Lucy Turner</name>
<name sortKey="Wells, George A" sort="Wells, George A" uniqKey="Wells G" first="George A" last="Wells">George A. Wells</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Boutron, Isabelle" sort="Boutron, Isabelle" uniqKey="Boutron I" first="Isabelle" last="Boutron">Isabelle Boutron</name>
</region>
</country>
<country name="Danemark"><noRegion><name sortKey="Hr Bjartsson, Asbj Rn" sort="Hr Bjartsson, Asbj Rn" uniqKey="Hr Bjartsson A" first="Asbj Rn" last="Hr Bjartsson">Asbj Rn Hr Bjartsson</name>
</noRegion>
</country>
<country name="Australie"><region name="Victoria (État)"><name sortKey="Waters, Elizabeth" sort="Waters, Elizabeth" uniqKey="Waters E" first="Elizabeth" last="Waters">Elizabeth Waters</name>
</region>
</country>
</tree>
</affiliations>
</record>

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Serveur d'exploration sur les relations entre la France et l'Australie

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

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	Serveur d'exploration sur les relations entre la France et l'Australie
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